Why mitochondrial energy is key for skin longevity
At the cellular level, our biological aging process is closely linked to our metabolic activity. As skin matures, some of its most important functions gradually decline: cellular turnover slows, collagen and elastin production decrease, the skin barrier weakens and becomes more vulnerable to external stressors... One of the key elements of this process is mitochondria. Let's discover how this works.
Mitochondria, the “powerhouses” of the cells
Inside each of our skin cells are small structures called mitochondria, often compared to "powerhouses". They play an essential role: producing the energy necessary for our cells to properly function. Mitochondria are responsible for generating nearly 90% of the energy required for cellular activity. This energy is produced in the form of adenosine triphosphate, or ATP. It fuels many biological processes, including cellular regeneration, which allows the skin to renew itself, repair itself, and maintain its structure over time. Mitochondrial energy is essential for cell renewal. Skin cells constantly divide and renew themselves to replace those that have been damaged or are reaching the end of their 28-day life cycle. This regeneration process helps maintain the skin's radiance, suppleness, and skin resilience.
What is the link between mitochondrial energy and skin aging?
When mitochondria function optimally, they provide cells with the energy needed to support this renewal and promote youthful-looking skin. But when mitochondrial function declines, skin cells produce less energy, making it harder for them to maintain optimal regeneration and repair mechanisms. This gradual change contributes to the appearance of visible signs of skin aging, such as loss of firmness, lack of radiance, or fine lines.
Mitochondria also play a key role in managing oxidative stress within skin cells. Environmental aggressors such as UV radiation and pollution can generate free radicals that damage cellular components. Healthy mitochondrial function helps cells better cope with this stress by supporting protective and repair mechanisms, contributing to stronger and more resilient skin.
Today, cosmetic research and skin longevity skincare are increasingly focused on ways to preserve cellular energy to support the skin aging process. By supporting mitochondrial function and cellular energy production, it is now possible to help the skin maintain its natural abilities to renew, repair, and resist external aggressors for longer.
How to support your skin’s longevity
What if your skincare routine was designed around biological skin age rather than chronological age? At Lancôme, we believe that our biological age does not refer to the number of years you have lived. Rather, it describes the state of your skin cells over time and your skin's ability to regenerate and repair itself, maintain its energy production, and preserve its structural integrity. With this in mind, how can you support your skin longevity and improve your biological age?
Choosing the right skincare
Skincare cannot reverse aging. But scientific research has shown that targeted formulas can help preserve skin health over time and help reduce some visible signs of aging. With the right product, you can act effectively on your skin's appearance and resilience, for a healthier and more youthful complexion. This means taking on a proactive rather than reactive approach to skin aging.
So, what ingredients should you look for in your new longevity skincare? Hyaluronic acid, peptides, vitamin C, niacinamide, and vitamin E are great ingredients to support hydration, antioxidant defense, and barrier function. Advanced technologies such as PDRN-inspired biomimetic molecules and NAD+ related research are also increasingly integrated into high-performance longevity formulas.
Absolue Longevity, a new range targeting skin longevity
Lancôme’s Absolue Longevity MD is a cutting-edge line in the world of longevity skincare. Based on our Longevity Integrative Science research, it was formulated with Mitopure® (Urolithin A), an active ingredient that is a highly pure form of Urolithin A, a postbiotic that reactivates mitochondria through a cellular renewal process called mitophagy.
Frequently asked questions
Can skincare really support cellular regeneration?
Skincare cannot fundamentally change the skin's natural renewal cycle, but it can support the biological processes involved in cellular regeneration, by strengthening the skin barrier, keeping it hydrated and protecting it against environmental stimuli that disrupt cell function.
What is Mitopure® and where does it come from?
Lancôme has partnered with Timeline, a leading Swiss company in the field of biotechnology and skin longevity. At the heart of this innovation partnership lies Mitopure®, a molecule developed by Timeline after fifteen years of scientific research.
How does Mitopure benefit the skin?
Mitopure® is a highly purified form of Urolithin A, a postbiotic molecule known for its role in supporting mitochondrial health. In skincare, this ingredient is studied for its ability to stimulate a natural cellular renewal process called mitophagy. This process helps remove damaged mitochondria and supports the formation of healthier ones, helping maintain efficient cellular energy production. By supporting mitochondrial function, Mitopure® aims to promote optimal cellular activity and help the skin maintain its ability to renew and repair itself.




